Blogging to the Bank Review
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BK virus associated nephropathy has become increasingly recognized as the cause of renal dysfunction and loss of the transplanted kidney in transplant patients.1 The BK virus is a human polyomavirus. Polyomaviruses are members of the Papovaviridae family, which are small, nonenveloped viruses with a closed, circular double DNA-stranded genome. Polyomaviruses are distinguished from papillomaviruses by a smaller virion size and a different genome size and organization. Polyomaviruses are ubiquitous in nature and can be isolated from a number of species. The human polyomaviruses were first isolated in 1971. They are named BK and JC after the initials of the patients in which they were first discovered. The BK virus was isolated from the urine of a renal transplant patient who developed ureteral stenosis postoperatively.
These words come from the pen of a Jewish prophet named Malachi. As the last spokesman of the Old Testament, he raised a troubling question. How can we take comfort in the love of God if we don't feel loved? What if circumstances seem to say that God is ignoring us, that He has abandoned us to our own pain, and that He is deliberately withholding from us what He could so easily grant?